Microplastics have always fascinated me, because I keep seeing article after article about how much microplastic exists around us, but far less strong evidence about its actual effects. That is not to say there are no effects, of course. Maybe we just have not found them yet.
A friend of mine worked on her bachelor’s thesis about the effects of microplastics on the immune system, specifically T cells. Her result was that the microplastic particles she studied were too large to interact with T cells.
She probably will not publish this result because she thinks it is not interesting enough. Classic file-drawer problem in academic science.
While I encourage her to do it anyways as a negative results is also interesting but she wanted results that are worthing of headlines in magazines.
> She probably will not publish this result because she thinks it is not interesting enough. Classic file-drawer problem in academic science.
It's truly insane that everyone in the academic class understands the fundamental problems of herding and sampling bias and yet every incentive is in place to do this.
There’s a transition point where things stop being micro plastics and become chemicals. Those molecules may be toxic but the interactions are distinct from microplastics.
Unknown to me, but something useful to know is that there is something smaller than microplastics called nanoplastics. The distinguishing factor is that nanoplastics are particles smaller than 1 micron, while microplastics are particles between 1 micron and around 5 millimeters. As your other respondent notes, at some point you're talking about single molecules. As plastics is an entire category and not a single thing, there's no one size where that happens, but some polymers have chains that are as little as 0.01 (1/100th of a) micron in size.
As far as I am aware, we have yet to have effective, replicable research on what if any biointeractions exist with nanoplastic particles, including single polymer chains.
> We assessed how reliable current measures are for trying to find microplastics in blood. And what we found is that lipids and fats will give you a false positive for polyethylene.
> We worked with an architect, and we built the lab pretty much from scratch. [...] So we ended up going with stainless steel. It was the only way to not have any plastics.
> I don’t think we’ve got really good evidence at all for what effects [microplastics particles on their own] might be having on human bodies. If we’re eating plastics, what size and what type of plastic can actually get into the bloodstream?
This is a great interview, though I'd caution against reading it like a literature review. It's just the views and opinions of a single (relevant and qualified) expert
Very nice to see someone actually looking at the issue objectively instead of the unholy blend of clickbait, shoddy "science" and either fear mongering or blind denialism we usually see.
Getting to the point where we're actually able to measure something real is good progress.
did read,
>e360: Do we really eat a credit card’s worth of plastic each week?
>Rauert: That has absolutely been debunked
and
>...we found is that lipids and fats will give you a false positive for polyethylene. Lipids are made up of the same building blocks as polyethylene, so when we analyze them, they look identical in our analysis instrument.
>I know it is easy to say we don’t have enough information yet, but we do know about [the health risks from] these chemicals that are in all the plastics that your food is wrapped in.
Not just because we can't measure it but because its hard to say what's due to the plastic and what's due to additives in the plastics
> And while we know a lot about the impact of chemicals added to plastic — such as phthalates, which have been shown to impact fertility, or bisphenols, which have been linked to Type 2 diabetes — we know very little about what effect the plastic particles themselves might be having.
I think hate of plastics is an emergent form of elitism.
Upwardly mobile middle/upper class people who've sort of "maxed out" the amount of personal identity they can buy with regular plastic things can unlock a new level of identity by deciding that plastics are bad for them and eliminating plastics from their life, a process which conveniently requires buying a whole new set of things that distinguish them from their peers.
This is the only way I can explain how irrational and inconsistent plastic-haters behavior is. There is so much invisible plastic in their life that they don't seem to care about.
> requires buying a whole new set of things that distinguish them from their peers
No, it requires buying a whole new set of things to fit in with and be accepted by their peers, to distinguish themselves from the outgroup, the plastic users.
I don’t necessarily believe this is some emergent elitism; I see it more as a modern religion with many many rules about eating and consumption (using plastic is now a sin).
Like any religion, sinners (for example plastic users) are mostly pitied because they are ignorant, but those who know and choose to use plastic anyway, well, it’s OK to hate them.
You could just liken it to any pop health, dietary, or environmental fad instead of trying to portray a banal "people turn consumer choices into personal identity/lifestyle" trend as a whole new type of phenomenon. Crunchy hippies shop organic and audiophiles buy gold-plated premium wires; every subculture has at least a little bit of superstition.
Even more so: plastics are not a specific chemical and they are not a specific material. Plastic is a category of materials that is very broad and very wide. You can make plastics out of almost anything. Therefore, to hate on plastics is to basically hate on an entire category of engineering and material design but not to actually know what a plastic is... sheer ignorance.
A friend of mine worked on her bachelor’s thesis about the effects of microplastics on the immune system, specifically T cells. Her result was that the microplastic particles she studied were too large to interact with T cells.
She probably will not publish this result because she thinks it is not interesting enough. Classic file-drawer problem in academic science.
While I encourage her to do it anyways as a negative results is also interesting but she wanted results that are worthing of headlines in magazines.
It's truly insane that everyone in the academic class understands the fundamental problems of herding and sampling bias and yet every incentive is in place to do this.
Learned a lot about making microfludic flow cells at least
Also, unfortunately, a result that industry and the anti-regulation crowd will use to say microplastics are harmless.
As far as I am aware, we have yet to have effective, replicable research on what if any biointeractions exist with nanoplastic particles, including single polymer chains.
> We assessed how reliable current measures are for trying to find microplastics in blood. And what we found is that lipids and fats will give you a false positive for polyethylene.
> We worked with an architect, and we built the lab pretty much from scratch. [...] So we ended up going with stainless steel. It was the only way to not have any plastics.
> I don’t think we’ve got really good evidence at all for what effects [microplastics particles on their own] might be having on human bodies. If we’re eating plastics, what size and what type of plastic can actually get into the bloodstream?
Getting to the point where we're actually able to measure something real is good progress.
and >...we found is that lipids and fats will give you a false positive for polyethylene. Lipids are made up of the same building blocks as polyethylene, so when we analyze them, they look identical in our analysis instrument. >I know it is easy to say we don’t have enough information yet, but we do know about [the health risks from] these chemicals that are in all the plastics that your food is wrapped in.
> And while we know a lot about the impact of chemicals added to plastic — such as phthalates, which have been shown to impact fertility, or bisphenols, which have been linked to Type 2 diabetes — we know very little about what effect the plastic particles themselves might be having.
Upwardly mobile middle/upper class people who've sort of "maxed out" the amount of personal identity they can buy with regular plastic things can unlock a new level of identity by deciding that plastics are bad for them and eliminating plastics from their life, a process which conveniently requires buying a whole new set of things that distinguish them from their peers.
This is the only way I can explain how irrational and inconsistent plastic-haters behavior is. There is so much invisible plastic in their life that they don't seem to care about.
Huh? You think it's hypocritical for people not to "seem to care about" things that, by your own definition, they are ignorant of?
No, it requires buying a whole new set of things to fit in with and be accepted by their peers, to distinguish themselves from the outgroup, the plastic users.
I don’t necessarily believe this is some emergent elitism; I see it more as a modern religion with many many rules about eating and consumption (using plastic is now a sin).
Like any religion, sinners (for example plastic users) are mostly pitied because they are ignorant, but those who know and choose to use plastic anyway, well, it’s OK to hate them.