7 comments

  • GenerWork 58 minutes ago
    This is great news! I think people forget how anti-skin cancer protocols even as simple as applying suntan lotion weren't as popular as recent as 50-60 years ago. Lots of "sun children" of the 50s and 60s are now feeling the repercussions of only applying baby oil and are getting hit with lots of melanoma.
    • Insanity 12 minutes ago
      +1. Also, just to call out, it doesn't need to be _warm_ for you to need sunblock. Even when it's cooler / cloudier out there you can still get skin damage. Look for UV rating rather than temperature. Conversely, it being hot doesn't imply high-UV either.
      • jjice 9 minutes ago
        I didn't know about the UV index or what it meant until like three years ago. It blows my mind I went that long without understanding. It was actually wonderful to learn that I could just see if I needed sunblock based on a 0-10 scale.

        We never wore sunscreen as kids because we didn't burn. I probably have had three sunburns in my life. Learned once I became an adult that that wasn't sound logic...

  • consumer451 47 minutes ago
    This appears to be a potentially huge win for health. The market has Moderna up 153%, which is some sort of validation I suppose.

    Related stories:

    https://www.fiercebiotech.com/biotech/merck-and-modernas-per...

    https://www.reuters.com/legal/litigation/merck-moderna-say-m...

    https://www.wsj.com/health/pharma/moderna-merck-vaccine-succ...

    • Jyaif 15 minutes ago
      oh nice. If it goes up another 100% I may not lose money on this stock anymore.
      • bpodgursky 5 minutes ago
        And if it doubles after that, I may even beat a passive S&P 500 investment.
      • consumer451 12 minutes ago
        I mean, this appears to be validation of mRNA in general, right?
  • epistasis 57 minutes ago
    Ever since I first heard of them a decade ago, it seemed that mRNA therapeutic vaccines were going to be the next wave of massive improvements in care. It's taken a bit longer than I had expected, and it's not that mRNA is the only way to make these sorts of vaccines, it's just so much better than the alternatives.

    I'm very very excited to see what comes next.

  • nearbyyak 5 minutes ago
    Huge, uplifting, news
  • MartinMond 46 minutes ago
    I listened to a great podcast on this just a month ago - too bad that I thought all of this would obviously be priced in already… https://virological.podigee.io/51-21-cancer-vaccines-how-the...
    • mapipolo 4 minutes ago
      Hard to price in the political factors now involved in Moderna's success or lack of success.
    • henry2023 33 minutes ago
      Even if you were to optimally price in all available information you still have uncertainty of what will actually happen. i.e. A 1 dollar coin flip has an expected value of 50c before it’s thrown and it will collapse either to zero or to one after the uncertainty is resolved.
    • bluGill 7 minutes ago
      I don't believe the efficient market hypothesis. However even if you do, new information has arrived and that will affect the price.
  • jambalaya8 1 hour ago
    [flagged]
    • tnel77 1 hour ago
      Why?
      • jimbo808 41 minutes ago
        People were assured that COVID vaccine mRNA would disappear within days and the spike protein would short-lived. Yet Yale-led researchers later detected circulating S1 and full-length spike as late as 709 days after vaccination.

        They also left the public in the dark about the risk of vaccine-associated myocarditis, especially in young males, many of whom experienced permanent heart tissue damage.

        That is a massive gap between what the public was told and what later evidence found. If a technology makes your cells produce a biologically active protein, regulators should establish where it goes, how long it can persist, and what prolonged exposure does before mass deployment.

        https://news.yale.edu/2025/02/19/immune-markers-post-vaccina... https://www.medrxiv.org/content/10.1101/2025.02.18.25322379v...

      • jambalaya8 54 minutes ago
        [flagged]
        • consumer451 48 minutes ago
          > (and yes, I have a background in this)

          Care to share what that is exactly?

  • reenorap 32 minutes ago
    I have 1000 shares of mRNA woohoo! For all the hate I have for the COVID vaccine, I still believe in the underlying technology and I put my money where my mouth was and bought around $20. I think this is just the first of many cancer treatments mRNA will bring and I’m very excited for the future of the technology.
    • Someone1234 27 minutes ago
      > For all the hate I have for the COVID vaccine

      Can you clarify that? It saved 100K+ lives even by incredibly conservative estimates, and allowed life to returned to normal at least a year earlier than otherwise.

      • declan_roberts 13 minutes ago
        I can't speak for other people but I was upset to enter a medical era where bureaucrats were forcing medical decisions on me. I was forced to get it or lose my job despite 1) working remotely, 2) having already had Covid and 3) being healthy and not at risk of Covid death but being the largest risk for myocarditis.
    • bhaak 20 minutes ago
      What are the reasons for the hate of the COVID vaccine?
      • declan_roberts 17 minutes ago
        Probably one of the most polarizing issues of the last 5 years.
        • Insanity 14 minutes ago
          I don't recall it being as polarizing outside of the US, where there was a larger group of anti-vaxxers to begin with. But that might be my "outside US" bubble.
      • alexlesuper 16 minutes ago
        Probably disinformation.